Isaac blinked, watching.

She sets it aside once it's empty, and her eyes dilate as the drug takes effect.
(It's a drug called Skooma, from Skyrim.)

(Lemme guess. Shes now either very high or very loopy.)

Isaac watched, smiling.

(Actually, it is very much like LSD. It causes intense hallucinations, and is very addictive. Khajiit are the ones who make the stuff, though they are immune to the ill effects due to centuries of their kind using it. They also make something called Moon Sugar, which is basically crack. The thing is, though, using Skooma is part of Khajiit culture. Smoke is going through a trip like LSD, which is far more intense than the trips she has on Skooma when she's in the world of Nirn.)
Smoke remains where she's sitting, looking around and rather confused.

(Huh.

That is very weird and specific.)

Isaac watched.

(Well, it's part of the lore.)
Smoke stays exactly where she is, not moving no matter what she sees during the trip.

(Fair)

Isaac grinned and poked her.

Smoke jerked away violently.

He pulled away, nervous.

Then, slowly, the trip ended, and Smoke collapsed on her back, panting.